Then the resulting serotonin goes completely rogue and basically changes function from stopping pain to just having a good time, signaling that you actually like the itch kind of, and the whole thing starts again. Blocking serotonin would therefore mess with everyday functions, like pain relief, and could have adverse effects on happiness.
Instead, Chen and his team went for even more specific territory, working on cells known as GRPR neuron to find that the receptor known as 5HT1A was the key to activating the itch-specific GRPR neurons in the spinal cord. First, you scratch, and that causes a sensation of pain. Then you make more serotonin to control the pain. Rief, W. How to use the new DSM-5 somatic symptom disorder diagnosis in research and practice: a critical evaluation and a proposal for modifications.
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Reprints and Permissions. Psychogenic itch. Transl Psychiatry 8, 52 Download citation. Received : 27 July Revised : 06 October Accepted : 01 November Published : 01 March Anyone you share the following link with will be able to read this content:. Sorry, a shareable link is not currently available for this article. Provided by the Springer Nature SharedIt content-sharing initiative. Journal of Medical Case Reports Advanced search. Skip to main content Thank you for visiting nature.
Download PDF. Subjects Depression Pathogenesis. Introduction Psychogenic itch is a diagnosis that is too frequently proposed by physicians, but patients diagnosed with psychogenic itch are too rarely referred to psychiatrists. What is itch? The burden of itch Like pain, nausea or asphyxiation, itch can cause major suffering. The frequency of psychogenic itch Psychiatrists commonly consider psychogenic itch a very rare condition because these patients usually prefer to consult dermatologists and avoid psychiatrists, as they initially associate the sensation with the skin rather than with a psychological suffering.
Definition At the individual level, patients need an adequate diagnosis. Table 1 Diagnostic criteria for functional itch disorder or psychogenic pruritus from the French Psychodermatology Group previously published in Acta Derm. Differential diagnosis In some patients, authentic somatic pruritus can be associated with psychogenic pruritus or can be aggravated by psychological factors that cannot be identified upon initial visit.
Physiopathology As reported above, the brain is a crucial organ for itch: the perception of itch is obviously not possible without the brain, and itch can sometimes originate in the brain in patients with disorders of the central nervous system 6 and those with psychological disorders.
Psychopathology Personality characteristics and depression could be identified as predictors of experimentally induced itch. Consequences of psychogenic itch Skin lesions In some patients, there is no scratching; however, usually psychogenic itch is accompanied by scratching, of which patients are more or less aware. Scratching lesions induced by psychogenic itch.
Full size image. Management Announcement of diagnosis The announcement of a diagnosis of psychogenic pruritus to a patient is not easy or anecdotal and should be made cautiously Pharmacological treatment There has been no clinical trial of treatments for psychogenic itch 57 , and the course of the disease is poorly known.
Psychological approach Any psychological intervention implies that the symptom is accepted as real and distressing for the patient Conclusions Although psychological factors can modulate itch in all patients, the specific diagnosis of psychogenic itch must be proposed cautiously. References 1. Article Google Scholar 3. Article Google Scholar 6. Article Google Scholar 7. Article Google Scholar 8. Luo, M. About Why scratching? Why itchiness?
Why is it hard to resist? Prevention Takeaway Share on Pinterest. What is an itch? Why does scratching feel good? Why do we get itchy? Why is it so hard to resist scratching an itch? How to stop scratching and prevent itching. The takeaway. Read this next. The 8 Best Remedies for Itching. Medically reviewed by Carissa Stephens, R. Itchy Skin at Night? Medically reviewed by Debra Rose Wilson, Ph.
Dry Skin vs. Medically reviewed by Susan Bard, MD. Medically reviewed by Avi Varma, MD.
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